Analytical and diagnostic characteristics of the high-sensitivity PATHFAST troponin I assay
نویسندگان
چکیده
منابع مشابه
Analytical validation of a high-sensitivity cardiac troponin T assay.
BACKGROUND We report the development of a novel high-sensitivity cardiac troponin T (hs-cTnT) assay, a modification of the Roche fourth-generation cTnT assay, and validation of the analytical performance of this assay. METHODS Validation included testing of analytical sensitivity, specificity, interferences, and precision. We established the 99th percentile cutoff from healthy reference popul...
متن کاملAnalytical characteristics of high-sensitivity cardiac troponin assays.
BACKGROUND Cardiac troponins I (cTnI) and T (cTnT) have received international endorsement as the standard biomarkers for detection of myocardial injury, for risk stratification in patients suspected of acute coronary syndrome, and for the diagnosis of myocardial infarction. An evidence-based clinical database is growing rapidly for high-sensitivity (hs) troponin assays. Thus, clarifications of...
متن کاملAnalytical performance of the i-STAT cardiac troponin I assay.
BACKGROUND This study determines the analytical characteristics of the i-STAT cardiac troponin I assay (cTnI; i-STAT, Princeton, NJ), a 10-min POC assay, designed to be performed at the bedside. METHODS Three different hospitals participated in a patient specimen and analytical validation study (n=186) for the i-STAT cTnI assay carried out in real time. A total of 186 whole blood specimens (l...
متن کاملAssay imprecision and 99th-percentile reference value of a high-sensitivity cardiac troponin I assay.
We undertook a performance evaluation and determination of the 99th-percentile reference value for the Siemens cTnI-Ultra with a fully characterized population that had undergone noninvasive cardiac imaging. Permission for the study was obtained from the local research ethics committee. Participants 45 years of age were randomly selected from the practice lists of 7 representative local communi...
متن کاملBiological and analytical variability of a novel high-sensitivity cardiac troponin T assay.
BACKGROUND High-sensitivity cardiac troponin assays will augment the frequency of increased results, making important the determination of reference change values to distinguish acute from chronic increases. We assessed short- and long-term biological variability of cardiac troponin T (cTnT) in healthy subjects with a novel high-sensitivity (hs) assay. METHODS We collected blood from 20 healt...
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ژورنال
عنوان ژورنال: Critical Care
سال: 2015
ISSN: 1364-8535
DOI: 10.1186/cc14239